USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TCPQ_HUMAN USC-OGP 2-DE database:  TCPQ_HUMAN TCPQ_HUMAN General information about the entry View entry in simple text format Entry name TCPQ_HUMAN Primary accession number P50990 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit theta; Short=TCP-1-theta; AltName: Full=CCT-theta; AltName: Full=Renal carcinoma antigen NY-REN-15;. Gene name Name=CCT8 Synonyms=C21orf112, CCTQ, KIAA0002 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0335: pI=5.34; Mw=61275 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1141: pI=5.49; Mw=61289 Cross-references UniProtKB/Swiss-Prot P50990; TCPQ_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TCPQ_HUMAN Primary accession number P50990 Secondary accession number(s) A6NN54 B4DEM7 B4DQH4 Q4VBP8 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 172) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit theta; Short=TCP-1-theta; AltName: Full=CCT-theta; AltName: Full=Renal carcinoma antigen NY-REN-15; Gene name Name=CCT8 Synonyms=C21orf112, CCTQ, KIAA0002 Encoded on Name=CCT8; Synonyms=C21orf112, CCTQ, KIAA0002 Keywords Acetylation; Alternative splicing; ATP-binding; Cell projection; Chaperone; Cilium; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D13627; BAA02792.2; ALT_INIT; mRNA EMBL D42052; BAA07652.1; ALT_SEQ; Genomic_DNA EMBL AF129075; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AK293705; BAG57138.1; -; mRNA EMBL AK298801; BAG60936.1; -; mRNA EMBL AL163249; CAB90433.1; -; Genomic_DNA EMBL BC072001; AAH72001.1; -; mRNA EMBL BC095470; AAH95470.1; -; mRNA EMBL Z37163; CAA85520.1; -; mRNA CCDS CCDS33528.1; -. [P50990-1]; . CCDS CCDS68180.1; -. [P50990-3]; . CCDS CCDS68181.1; -. [P50990-2]; . PIR PC4021; PC4021; . RefSeq NP_001269836.1; NM_001282907.1. [P50990-2]; . RefSeq NP_001269838.1; NM_001282909.1. [P50990-3]; . RefSeq NP_006576.2; NM_006585.3. [P50990-1]; . UniGene Hs.125113; -; . ProteinModelPortal P50990; -; . BioGrid 115933; 180; . DIP DIP-38124N; -; . IntAct P50990; 112; . MINT MINT-1152593; -; . STRING 9606.ENSP00000286788; -; . iPTMnet P50990; -; . PhosphoSitePlus P50990; -; . SwissPalm P50990; -; . BioMuta CCT8; -; . DMDM 9988062; -; . OGP P50990; -; . REPRODUCTION-2DPAGE IPI00784090; -; . REPRODUCTION-2DPAGE P50990; -; . EPD P50990; -; . MaxQB P50990; -; . PaxDb P50990; -; . PeptideAtlas P50990; -; . PRIDE P50990; -; . TopDownProteomics P50990-1; -. [P50990-1]; . Ensembl ENST00000286788; ENSP00000286788; ENSG00000156261. [P50990-1]; . Ensembl ENST00000540844; ENSP00000442730; ENSG00000156261. [P50990-3]; . Ensembl ENST00000626972; ENSP00000486921; ENSG00000156261. [P50990-2]; . GeneID 10694; -; . KEGG hsa:10694; -; . UCSC uc002ynb.5; human. [P50990-1]; . CTD 10694; -; . DisGeNET 10694; -; . GeneCards CCT8; -; . HGNC HGNC:1623; CCT8; . HPA HPA018520; -; . HPA HPA021051; -; . HPA HPA029426; -; . neXtProt NX_P50990; -; . OpenTargets ENSG00000156261; -; . PharmGKB PA26186; -; . eggNOG KOG0362; Eukaryota; . eggNOG ENOG410XPXR; LUCA; . GeneTree ENSGT00550000074783; -; . HOGENOM HOG000226734; -; . HOVERGEN HBG103107; -; . InParanoid P50990; -; . KO K09500; -; . OMA KYGLMAV; -; . OrthoDB EOG091G05WZ; -; . PhylomeDB P50990; -; . TreeFam TF105699; -; . Reactome R-HSA-389957; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome R-HSA-389960; Formation of tubulin folding intermediates by CCT/TriC; . Reactome R-HSA-390450; Folding of actin by CCT/TriC; . Reactome R-HSA-390471; Association of TriC/CCT with target proteins during biosynthesis; . Reactome R-HSA-5620922; BBSome-mediated cargo-targeting to cilium; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-6814122; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; . ChiTaRS CCT8; human; . GeneWiki CCT8; -; . GenomeRNAi 10694; -; . PRO PR:P50990; -; . Proteomes UP000005640; Chromosome 21; . Bgee ENSG00000156261; -; . CleanEx HS_CCT8; -; . ExpressionAtlas P50990; baseline and differential; . Genevisible P50990; HS; . GO GO:0035578; C:azurophil granule lumen; TAS:Reactome; . GO GO:0044297; C:cell body; IEA:Ensembl; . GO GO:0005813; C:centrosome; IDA:MGI; . GO GO:0005832; C:chaperonin-containing T-complex; IDA:UniProtKB; . GO GO:0005929; C:cilium; IEA:UniProtKB-KW; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0002199; C:zona pellucida receptor complex; IEA:Ensembl; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0042623; F:ATPase activity; coupled; TAS:ProtInc GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0044183; F:protein binding involved in protein folding; IBA:GO_Central; . GO GO:0051082; F:unfolded protein binding; IBA:GO_Central; . GO GO:0006458; P:'de novo' protein folding; IBA:GO_Central; . GO GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl; . GO GO:0061077; P:chaperone-mediated protein folding; IBA:GO_Central; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0046931; P:pore complex assembly; IEA:Ensembl; . GO GO:1904851; P:positive regulation of establishment of protein localization to telomere; IMP:BHF-UCL; . GO GO:1904871; P:positive regulation of protein localization to Cajal body; IMP:BHF-UCL; . GO GO:1904874; P:positive regulation of telomerase RNA localization to Cajal body; IMP:BHF-UCL; . GO GO:0032212; P:positive regulation of telomere maintenance via telomerase; IMP:BHF-UCL; . GO GO:0006457; P:protein folding; TAS:Reactome; . GO GO:0050821; P:protein stabilization; IMP:BHF-UCL; . GO GO:1901998; P:toxin transport; IEA:Ensembl; . CDD cd03341; TCP1_theta; 1; . Gene3D 1.10.560.10; -; 2; . Gene3D 3.30.260.10; -; 2; . Gene3D 3.50.7.10; -; 1; . InterPro IPR012721; Chap_CCT_theta; . InterPro IPR017998; Chaperone_TCP-1; . InterPro IPR002194; Chaperonin_TCP-1_CS; . InterPro IPR002423; Cpn60/TCP-1; . InterPro IPR027409; GroEL-like_apical_dom; . InterPro IPR027413; GROEL-like_equatorial; . InterPro IPR027410; TCP-1-like_intermed; . Pfam PF00118; Cpn60_TCP1; 1; . PRINTS PR00304; TCOMPLEXTCP1; . SUPFAM SSF52029; SSF52029; 1; . TIGRFAMs TIGR02346; chap_CCT_theta; 1; . PROSITE PS00750; TCP1_1; 1; . PROSITE PS00751; TCP1_2; 1; . PROSITE PS00995; TCP1_3; 1; .

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